Italy is set to lock down at least 10 million people in the region of Lombardy and 11 provinces in the north and the east of the country.
The mandatory quarantine will last until early April.
The dramatic escalation in the country’s efforts to contain the new deadly coronavirus will close gyms, pools, museums and ski resorts.
Italy is Europe’s worst hit-country and reported a steep rise in virus infections on Saturday.
The new measures could take effect as early as Sunday and will last until 3 April.
The death toll in Italy has passed 230, with officials reporting more than 50 deaths in 24 hours. The number of confirmed cases jumped by more than 1,200 to 5,883 on Saturday.
The measures published in a draft government decree were obtained by Italian newspaper Corriere della Sera.
They are set to be signed in the coming hours, reports the BBC’s Mark Lowen.
The whole northern region of Lombardy, home to 10 million people and Italy’s financial centre Milan, will be closed off except to emergency access, and 11 provinces including Venice, Parma and Modena will be affected.
Until now around 50,000 people in northern Italy had been affected by quarantine measures.
Night clubs, gyms, swimming pools, museums and ski resorts will be closed.
Restaurants and cafes can open but customers must sit at least a metre apart.
People will be told to stay home as much as possible, and those who break the quarantine could face three months in jail.
Sports competitions will close to the public, and the president of Italy’s football players’ union has called for all football to stop.
The World Health Organization has advised Italy to strongly focus on virus containment measures as infections spread in the country.
Leading Italian politician Nicola Zingaretti said on Saturday he had tested positive for the virus.
“I am fine but I will have to stay home for the next few days,” the leader of Italy’s centre-left Democratic Party (PD) said in a Facebook post.
The country has said it will start recruiting retired doctors in an effort to combat the escalating outbreak.
Elsewhere, Iran has confirmed almost 6,000 infections and 145 deaths, and the number of cases worldwide has passed 10,000, officials say.
A second MP was reportedly among those to have died in Iran, where health officials fear the number of cases may actually be much higher.
There have so far been nearly 3,500 coronavirus deaths recorded worldwide. The majority have been in China, where the virus originated in December.
The head of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, has called the spread of the virus “deeply concerning” and urged all countries to make containment “their highest priority”.
In other developments:
- A hotel used as a coronavirus quarantine facility in the Chinese city of Quanzhou collapsed
- Pope Francis is to deliver Sunday’s Angelus Prayer by livestream to avoid the usual crowds forming
- A cruise ship with 3,533 passengers and crew is being held off the coast near San Francisco after 21 people tested positive for the disease. All on board are being tested
- The US death toll rose to 19 as Washington state reported two more fatalities. The Governor of New York state Andrew Cuomo declared a state of emergency there as cases jumped from 44 on Friday to 76
- Egypt has confirmed 33 new cases on a cruise ship on the River Nile, taking the total number of people infected on board to 45. Officials say those affected are Egyptian and are not displaying symptoms
- The popular South by Southwest music festival in Austin, Texas, has been cancelled
- Malta, Serbia, Slovakia, Peru and Togo reported their first cases of the virus.
What’s the latest on cases?
In Iran, 21 people are reported to have died as a result of coronavirus in the past day.
A spokesman for Iran’s health ministry, Kianoush Jahanpour, said in a televised news conference on Saturday that more than 16,000 people were currently being tested in the country.
He added that 1,669 people with the illness had recovered.
The WHO’s representative in Iran, Dr Christoph Hamelmann, said Iran was making tremendous progress at its hospitals, with facilities made available for treatment in every province.
Among other countries to report a rise in the total number of cases are: France (to 949); Germany (795); Spain (441); the UK (206); the Netherlands (188).
More than 80,000 people have been infected with coronavirus in China since its emergence in the city of Wuhan, Hubei province. Globally the number of infections stands at more than 100,000.
You might be interested in watching:
Have you or someone you know been affected by coronavirus? Share your experiences by emailing.
Please include a contact number if you are willing to speak to a BBC journalist. You can also contact us in the following ways: